YB. TUN TAN SIEW SIN

Minister for Commerce and Industry
31.08.1957 - 21.01.1959

YB. TUN DR. ISMAIL BIN DATUK HJ. ABDUL RAHMAN

Minister for Commerce and Industry
20.09.1959 - 17.11.1959
(Renamed Minister of Trade and Industry with effect from 11.05.1972)
03.01.1973 - 12.08.1973

YB. TAN SRI MOHAMED KHIR BIN JOHARI

Minister for Commerce and Industry
18.11.1959 - 09.10.1962

YB. DR. LIM SWEE AUN

Minister for Commerce and Industry
10.10.1962 - 03.06.1969

YB. TUN HUSSEIN BIN DATO' ONN

Minister of Trade and Industry
13.08.1973 - 14.09.1974

YB. TAN SERI HAMZAH BIN ABU SAMAH

Minister of Trade and Industry
05.09.1974 - 31.12.1977

YB. TUN DR. MAHATHIR BIN MOHAMED

Minister of Trade and Industry
01.01.1978 - 16.07.1981

YM TENGKU TAN SRI AHMAD RITHAUDDEN BIN TENGKU ISMAIL

Minister of Trade and Industry
17.07.1981 - 16.07.1984

YM TENGKU RAZALEIGH BIN TENGKU MOHD. HAMZAH

Minister of Trade and Industry
17.07.1984 - 28.04.1987

YB. DATO' SERI RAFIDAH BT. AZIZ

Minister of Trade and Industry
(Renamed Minister of International Trade and Industry with effect from 27.10.1990)
20.05.1987 - 17.03.2008

YB. TAN SRI MUHYIDDIN BIN HJ. MOHD YASSIN

Minister of International Trade and Industry 
18.03.2008 - 09.04.2009 

YB. DATO' SRI MUSTAPA BIN MOHAMED

Minister of International Trade and Industry 
09.04.2009 - Now